human PLCZ1 Over-expression AAV

Name
AAV-h-PLCZ1

Cat No
AAV-219142

Availability
4-5 weeks

This is an AAV expressing Human PLCZ1.

AAV-219142

AAV-h-PLCZ1

Ready-to-use AAV expressing Human PLCZ1 (phospholipase C zeta 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NYD-SP27; PLC-zeta-1; PLCzeta; SPGF17

Description (Vector)

PLCZ1 is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants.

Gene ID

89869

Gene Name (Vector)

phospholipase C zeta 1

Gene Symbol

PLCZ1

HGNC ID

HGNC:19218

ORF Size (aa)

1248

ORF Size (bp)

1248 bp

RefSeq ID

NM_033123

RefSeq Synonyms

NM_033123, NM_001330774, NM_001330769, BC125067,

Species

human

UniGene ID

Hs.97542

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.