human PLCD1 Over-expression AAV

Name
AAV-h-PLCD1

Cat No
AAV-219121

Availability
4-5 weeks

This is an AAV expressing Human PLCD1.

AAV-219121

AAV-h-PLCD1

Ready-to-use AAV expressing Human PLCD1 (phospholipase C delta 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NDNC3; PLC-III

Description (Vector)

PLCD1 encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

5333

Gene Name (Vector)

phospholipase C delta 1

Gene Symbol

PLCD1

HGNC ID

HGNC:9060

ORF Size (aa)

2271

ORF Size (bp)

2271 bp

RefSeq ID

NM_006225

RefSeq Synonyms

NM_006225, NM_001130964, BC050382,

Species

human

UniGene ID

Hs.80776

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.