human PLA2G15 Over-expression AAV

Name 
AAV-h-PLA2G15
Cat No 
AAV-219060
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLA2G15.

AAV-219060
AAV-h-PLA2G15

Ready-to-use AAV expressing Human PLA2G15 (phospholipase A2 group XV). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACS; GXVPLA2; LLPL; LPLA2; LYPLA3
Description (Vector)
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
Gene ID
23659
Gene Name (Vector)
phospholipase A2 group XV
Gene Symbol
PLA2G15
HGNC ID
HGNC:17163
ORF Size (aa)
1239
ORF Size (bp)
1239 bp
RefSeq ID
NM_012320
RefSeq Synonyms
NM_012320, BC062605, BC011640,
Species
human
UniGene ID
Hs.632199

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.