human PKMYT1 Over-expression AAV

Name 
AAV-h-PKMYT1
Cat No 
AAV-219038
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PKMYT1.

AAV-219038
AAV-h-PKMYT1

Ready-to-use AAV expressing Human PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; MYT1; myt1 kinase; PPP1R126; protein phosphatase 1, regulatory subunit 126
Description (eCommerce)
MYT1 (membrane associated tyrosine/threonine protein kinase 1) is is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. MYT is associated with the membrane throughout the cell cycle, and its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of MYT1 [taken from NCBI Entrez Gene (GeneID:9088)].
Description (Vector)
PKMYT1 encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
9088
Gene Name (eCommerce)
protein kinase, membrane associated tyrosine/threonine 1
Gene Name (Vector)
protein kinase, membrane associated tyrosine/threonine 1
Gene Symbol
PKMYT1
HGNC ID
HGNC:29650
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
Protein Name (eCommerce)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
RefSeq ID
NM_004203
RefSeq Synonyms
NM_182687, NM_004203, NM_001258451, NM_001258450, BC160025,
Research Areas
Cell Cycle,Golgi Apparatus,Kinase/Phosphatase,Meiosis
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,signal_transduction
Species
human
Target Sentence
MYT1 (membrane associated tyrosine/threonine protein kinase 1) is is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. MYT is associated with the membrane throughout the cell cycle, and its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of MYT1 [taken from NCBI Entrez Gene (GeneID:9088)].
UniGene ID
Hs.77783
UniProt ID (eCommerce)
Q99640

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.