human PIGQ Over-expression AAV

Name
AAV-h-PIGQ

Cat No
AAV-218919

Availability
4-5 weeks

This is an AAV expressing Human PIGQ.

AAV-218919

AAV-h-PIGQ

Ready-to-use AAV expressing Human PIGQ (phosphatidylinositol glycan anchor biosynthesis class Q). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

c407A10.1; GPI1

Description (Vector)

PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

9091

Gene Name (Vector)

phosphatidylinositol glycan anchor biosynthesis class Q

Gene Symbol

PIGQ

HGNC ID

HGNC:14135

ORF Size (aa)

2283

ORF Size (bp)

2283 bp

RefSeq ID

NM_004204

RefSeq Synonyms

NM_148920, NM_004204, BC006377,

Species

human

UniGene ID

Hs.709562

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.