human PHF17 Over-expression AAV

Name 
AAV-h-PHF17
Cat No 
AAV-218807
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human JADE1.

AAV-218807
AAV-h-PHF17

Ready-to-use AAV expressing Human JADE1 (jade family PHD finger 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
gene for apoptosis and differentiation in epithelia; jade family PHD finger protein 1; PHD finger protein 17; PHD protein Jade-1; PHF17; protein Jade-1
Description (eCommerce)
Gene for apoptosis and differentiation-1 (Jade-1) is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3, and is responsible for the bulk of histone H4 acetylation in vivo. As a transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Jade-1 also Promotes apoptosis and may act as a renal tumor suppressor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q6IE81].
Gene ID
79960
Gene Name (eCommerce)
jade family PHD finger 1
Gene Name (Vector)
jade family PHD finger 1
Gene Symbol
JADE1
HGNC ID
HGNC:30027
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
Protein Name (eCommerce)
Protein Jade-1
RefSeq ID
NM_024900
RefSeq Synonyms
NM_199320, NM_024900, NM_001287443, NM_001287442, NM_001287441, NM_001287440, NM_001287439, NM_001287437, BC032376,
Research Areas
Apoptosis,Histone Modification,Mitochondrion,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Gene for apoptosis and differentiation-1 (Jade-1) is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3, and is responsible for the bulk of histone H4 acetylation in vivo. As a transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Jade-1 also Promotes apoptosis and may act as a renal tumor suppressor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q6IE81].
UniGene ID
Hs.12420
UniProt ID (eCommerce)
Q6IE81

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.