human PEA15 Over-expression AAV

Name 
AAV-h-PEA15
Cat No 
AAV-218587
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PEA15.

AAV-218587
AAV-h-PEA15

Ready-to-use AAV expressing Human PEA15 (phosphoprotein enriched in astrocytes 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED
Description (Vector)
PEA15 encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.
Gene ID
8682
Gene Name (Vector)
phosphoprotein enriched in astrocytes 15
Gene Symbol
PEA15
HGNC ID
HGNC:8822
ORF Size (aa)
393
RefSeq ID
NM_003768
RefSeq Synonyms
NM_003768, NM_001297578, NM_001297577, NM_001297576, BC022554, BC010469, BC002426,
Species
human
UniGene ID
Hs.517216

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.