human PDSS1 Over-expression AAV

Name 
AAV-h-PDSS1
Cat No 
AAV-218557
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PDSS1.

AAV-218557
AAV-h-PDSS1

Ready-to-use AAV expressing Human PDSS1 (decaprenyl diphosphate synthase subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COQ1; COQ10D2; DPS; hDPS1; SPS; TPRT; TPT; TPT 1
Description (Vector)
PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.
Gene ID
23590
Gene Name (Vector)
decaprenyl diphosphate synthase subunit 1
Gene Symbol
PDSS1
HGNC ID
HGNC:17759
ORF Size (aa)
921
ORF Size (bp)
921 bp
RefSeq ID
NM_014317
RefSeq Synonyms
NM_014317, NM_001321979, NM_001321978, BC063635,
Species
human
UniGene ID
Hs.558468

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.