human PDLIM2 Over-expression AAV

Name
AAV-h-PDLIM2

Cat No
AAV-218542

Availability
4-5 weeks

This is an AAV expressing Human PDLIM2.

AAV-218542

AAV-h-PDLIM2

Ready-to-use AAV expressing Human PDLIM2 (PDZ and LIM domain 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MYSTIQUE; SLIM

Description (Vector)

PDLIM2 encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

64236

Gene Name (Vector)

PDZ and LIM domain 2

Gene Symbol

PDLIM2

HGNC ID

HGNC:13992

ORF Size (aa)

1059

ORF Size (bp)

1059 bp

RefSeq ID

NM_021630

RefSeq Synonyms

NM_198042, NM_176871, NM_021630, BC071774, BC021556,

Species

human

UniGene ID

Hs.632034

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.