human PDE4D Over-expression AAV

Name 
AAV-h-PDE4D
Cat No 
AAV-218479
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PDE4D.

AAV-218479
AAV-h-PDE4D

Ready-to-use AAV expressing Human PDE4D (phosphodiesterase 4D). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D6; DPDE3; HSPDE4D; PDE43; PDE4DN2; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); STRK1; testicular tissue protein Li 136
Description (eCommerce)
PDE4D (cAMP-specific 3’,5’-cyclic phosphodiesterase 4D) is one of four mammalian counterparts to the fruit fly 'dunce' gene. PDE4D has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types [taken from NCBI Entrez Gene (GeneID: 5144)].
Description (Vector)
PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. PDE4D uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Gene ID
5144
Gene Name (eCommerce)
phosphodiesterase 4D
Gene Name (Vector)
phosphodiesterase 4D
Gene Symbol
PDE4D
HGNC ID
HGNC:8783
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1557
ORF Size (bp)
1557 bp
Protein Name (eCommerce)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
RefSeq ID
NM_006203
RefSeq Synonyms
NM_006203, NM_001197223, NM_001197222, NM_001197221, NM_001197220, NM_001197219, NM_001197218, NM_001165899, NM_001104631, BC036319, BC008390,
Research Areas
Cardiovascular,Cytoskeleton,GPCR Signaling,Metabolism/Metabolic Process,Neurobiology,Signal Transduction,TSH Signaling
Research Areas (Faceted)
cardiovascular,signal_transduction,cell_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
PDE4D (cAMP-specific 3’,5’-cyclic phosphodiesterase 4D) is one of four mammalian counterparts to the fruit fly 'dunce' gene. PDE4D has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types [taken from NCBI Entrez Gene (GeneID: 5144)].
UniGene ID
Hs.117545
UniProt ID (eCommerce)
Q08499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.