human PCDHA6 Over-expression AAV

Name 
AAV-h-PCDHA6
Cat No 
AAV-218338
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PCDHA6.

AAV-218338
AAV-h-PCDHA6

Ready-to-use AAV expressing Human PCDHA6 (protocadherin alpha 6). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
Description (Vector)
PCDHA6 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Gene ID
56142
Gene Name (Vector)
protocadherin alpha 6
Gene Symbol
PCDHA6
HGNC ID
HGNC:8672
ORF Size (aa)
2853
ORF Size (bp)
2853 bp
RefSeq ID
NM_018909
RefSeq Synonyms
NM_031849, NM_031848, NM_018909, BC036674,
Species
human
UniGene ID
Hs.199343

Recently Viewed Products

AAV-h-PPIA

Cat No: AAV-219535

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.