human P2RX7 Over-expression AAV

Name 
AAV-h-P2RX7
Cat No 
AAV-218051
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human P2RX7.

AAV-218051
AAV-h-P2RX7

Ready-to-use AAV expressing Human P2RX7 (purinergic receptor P2X 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
P2X7
Description (Vector)
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Gene ID
5027
Gene Name (Vector)
purinergic receptor P2X 7
Gene Symbol
P2RX7
HGNC ID
HGNC:8537
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_002562
RefSeq Synonyms
NM_002562, BC011913, BC007679,
Species
human
UniGene ID
Hs.507102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.