rat EIF3J shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Eif3j.
shADV-295113
Ad-r-EIF3J-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Eif3j (eukaryotic translation initiation factor 3, subunit J). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Eif3s1
Description (Vector)
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
Gene ID
691947
Gene Name (Vector)
eukaryotic translation initiation factor 3, subunit J
Gene Symbol
Eif3j
ORF Size (aa)
780
ORF Size (bp)
780 bp
RefSeq ID
NM_001077670
RefSeq Synonyms
NM_001077670, BC127509,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.