rat CRBN shRNA silencing Adenovirus

Name
Ad-r-CRBN-shRNA

Cat No
shADV-295064

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Crbn.

shADV-295064

Ad-r-CRBN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Crbn (cereblon). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Component of some DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8. In the complex, may act as a substrate receptor. Regulates the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.

Gene ID

297498

Gene Name (Vector)

cereblon

Gene Symbol

Crbn

ORF Size (aa)

1338

ORF Size (bp)

1338 bp

RefSeq ID

NM_001015003

RefSeq Synonyms

NM_001015003, BC127455,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.