rat MYD88 shRNA silencing Adenovirus

Name 
Ad-r-MYD88-shRNA
Cat No 
shADV-293909
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Myd88.

shADV-293909
Ad-r-MYD88-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Myd88 (myeloid differentiation primary response 88). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
95
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity).
Gene ID
301059
Gene Name (Vector)
myeloid differentiation primary response 88
Gene Symbol
Myd88
ORF Size (aa)
891
ORF Size (bp)
891 bp
RefSeq ID
NM_198130
RefSeq Synonyms
NM_198130, BC097266,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.