rat ADIPOQ shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Adipoq.
shADV-293141
Ad-r-ADIPOQ-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Adipoq (adiponectin, C1Q and collagen domain containing). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Acdc; Acrp30
Description (Vector)
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Gene ID
246253
Gene Name (Vector)
adiponectin, C1Q and collagen domain containing
Gene Symbol
Adipoq
ORF Size (aa)
735
ORF Size (bp)
735 bp
RefSeq ID
NM_144744
RefSeq Synonyms
NM_144744, BC092565,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.