rat FTS shRNA silencing Adenovirus

Name 
Ad-r-FTS-shRNA
Cat No 
shADV-292966
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Aktip.

shADV-292966
Ad-r-FTS-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Aktip (AKT interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
89
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Fts
Description (Vector)
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Gene ID
291906
Gene Name (Vector)
AKT interacting protein
Gene Symbol
Aktip
ORF Size (aa)
879
ORF Size (bp)
879 bp
RefSeq ID
NM_001011926
RefSeq Synonyms
NM_001011926, BC089985,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.