rat SPIB shRNA silencing Adenovirus

Name
Ad-r-SPIB-shRNA

Cat No
shADV-292839

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Spib.

shADV-292839

Ad-r-SPIB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Spib (Spi-B transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.

Gene ID

499146

Gene Name (Vector)

Spi-B transcription factor

Gene Symbol

Spib

ORF Size (aa)

810

RefSeq ID

NM_001024286

RefSeq Synonyms

NM_001024286, BC089881,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.