rat FAIM3 shRNA silencing Adenovirus

Name 
Ad-r-FAIM3-shRNA
Cat No 
shADV-292771
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Fcmr.

shADV-292771
Ad-r-FAIM3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Fcmr (Fc fragment of IgM receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Faim3; Toso
Description (Vector)
FAIM3 may play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Gene ID
548326
Gene Name (Vector)
Fc fragment of IgM receptor
Gene Symbol
Fcmr
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_001014843
RefSeq Synonyms
NM_001014843, BC088197,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.