rat UBE2V2 shRNA silencing Adenovirus

Name 
Ad-r-UBE2V2-shRNA
Cat No 
shADV-292564
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Ube2v2.

shADV-292564
Ad-r-UBE2V2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ube2v2 (ubiquitin conjugating enzyme E2 V2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
98
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MMS2
Description (Vector)
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Gene ID
287927
Gene Name (Vector)
ubiquitin conjugating enzyme E2 V2
Gene Symbol
Ube2v2
ORF Size (aa)
438
RefSeq ID
NM_183052
RefSeq Synonyms
NM_183052, BC087593,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.