rat CFB shRNA silencing Adenovirus

Name
Ad-r-CFB-shRNA

Cat No
shADV-292471

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Cfb.

shADV-292471

Ad-r-CFB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Cfb (complement factor B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Bf; Da1-24

Description (Vector)

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Gene ID

294257

Gene Name (Vector)

complement factor B

Gene Symbol

Cfb

ORF Size (aa)

2286

ORF Size (bp)

2286 bp

RefSeq ID

NM_212466

RefSeq Synonyms

NM_212466, BC087089,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.