rat APH1A shRNA silencing Adenovirus

Name 
Ad-r-APH1A-shRNA
Cat No 
shADV-292466
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Aph1a.

shADV-292466
Ad-r-APH1A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Aph1a (aph-1 homolog A, gamma secretase subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
96
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RGD1311546
Description (Vector)
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Gene ID
365872
Gene Name (Vector)
aph-1 homolog A, gamma secretase subunit
Gene Symbol
Aph1a
ORF Size (aa)
744
ORF Size (bp)
744 bp
RefSeq ID
NM_001014255
RefSeq Synonyms
NM_001014255, BC087081,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.