rat NCDN shRNA silencing Adenovirus

Name
Ad-r-NCDN-shRNA

Cat No
shADV-292290

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Ncdn.

shADV-292290

Ad-r-NCDN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ncdn (neurochondrin). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Norbin

Description (Vector)

Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.

Gene ID

89791

Gene Name (Vector)

neurochondrin

Gene Symbol

Ncdn

ORF Size (aa)

2190

ORF Size (bp)

2190 bp

RefSeq ID

NM_053543

RefSeq Synonyms

NM_053543, BC087000,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.