rat TPM1 shRNA silencing Adenovirus

Name
Ad-r-TPM1-shRNA

Cat No
shADV-291965

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Tpm1.

shADV-291965

Ad-r-TPM1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Tpm1 (tropomyosin 1, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Alpha-tm; Tma2; Tmsa

Description (Vector)

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Gene ID

24851

Gene Name (Vector)

tropomyosin 1, alpha

Gene Symbol

Tpm1

ORF Size (aa)

747

ORF Size (bp)

747 bp

RefSeq ID

NM_019131

RefSeq Synonyms

NM_019131, NM_001301736, NM_001301342, NM_001301336, NM_001034075, NM_001034074, NM_001034073, NM_001034072, NM_001034071, NM_001034070, NM_001034069, NM_001034068, BC078780,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.