human KMO Over-expression AAV

Name 
AAV-h-KMO
Cat No 
AAV-217439
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KMO.

AAV-217439
AAV-h-KMO

Ready-to-use AAV expressing Human KMO (kynurenine 3-monooxygenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ317G22.1
Description (Vector)
KMO encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.
Gene ID
8564
Gene Name (Vector)
kynurenine 3-monooxygenase
Gene Symbol
KMO
HGNC ID
HGNC:6381
ORF Size (aa)
1224
ORF Size (bp)
1224 bp
RefSeq ID
NM_003679
RefSeq Synonyms
NM_003679, BC005297,
Species
human
UniGene ID
Hs.409081

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.