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rat PI4K2B shRNA silencing Adenovirus

Name 
Ad-r-PI4K2B-shRNA
Cat No 
shADV-291112
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Pi4k2b.

shADV-291112
Ad-r-PI4K2B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Pi4k2b (phosphatidylinositol 4-kinase type 2 beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
98
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Gene ID
305419
Gene Name (Vector)
phosphatidylinositol 4-kinase type 2 beta
Gene Symbol
Pi4k2b
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_001005883
RefSeq Synonyms
NM_001005883, BC083668,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.