rat MDM4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Mdm4.
shADV-291094
Ad-r-MDM4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Mdm4 (MDM4, p53 regulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Gene ID
304798
Gene Name (Vector)
MDM4, p53 regulator
Gene Symbol
Mdm4
ORF Size (aa)
1473
ORF Size (bp)
1473 bp
RefSeq ID
NM_001012026
RefSeq Synonyms
NM_001012026, BC083647,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.