rat MAS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Mas1.
shADV-290975
Ad-r-MAS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Mas1 (MAS1 proto-oncogene, G protein-coupled receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
c-mas; Mgra
Description (Vector)
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Gene ID
25153
Gene Name (Vector)
MAS1 proto-oncogene, G protein-coupled receptor
Gene Symbol
Mas1
ORF Size (aa)
975
RefSeq ID
NM_012757
RefSeq Synonyms
NM_012757, BC078884,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.