rat MFN2 shRNA silencing Adenovirus

Name
Ad-r-MFN2-shRNA

Cat No
shADV-290636

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Mfn2.

shADV-290636

Ad-r-MFN2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Mfn2 (mitofusin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HSG

Description (Vector)

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation.

Gene ID

64476

Gene Name (Vector)

mitofusin 2

Gene Symbol

Mfn2

ORF Size (aa)

2274

ORF Size (bp)

2274 bp

RefSeq ID

NM_130894

RefSeq Synonyms

NM_130894, BC070880,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.