rat LEPROT shRNA silencing Adenovirus

Name 
Ad-r-LEPROT-shRNA
Cat No 
shADV-290571
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Leprot.

shADV-290571
Ad-r-LEPROT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Leprot (leptin receptor overlapping transcript). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
79
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Ob-Rgrp; Obrgrp
Description (Vector)
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
Gene ID
56766
Gene Name (Vector)
leptin receptor overlapping transcript
Gene Symbol
Leprot
ORF Size (aa)
396
RefSeq ID
NM_020099
RefSeq Synonyms
NM_020099, BC062003,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.