rat PTBP1 shRNA silencing Adenovirus

Name
Ad-r-PTBP1-shRNA

Cat No
shADV-290482

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Ptbp1.

shADV-290482

Ad-r-PTBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ptbp1 (polypyrimidine tract binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Ptb; PTB1; Pybp; Pybp1; Pybp2

Description (Vector)

Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.

Gene ID

29497

Gene Name (Vector)

polypyrimidine tract binding protein 1

Gene Symbol

Ptbp1

ORF Size (aa)

1671

ORF Size (bp)

1671 bp

RefSeq ID

NM_001271057

RefSeq Synonyms

NM_022516, NM_001271057, BC061858,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.