mouse NFX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nfx1.
shADV-280912
Ad-m-NFX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nfx1 (nuclear transcription factor, X-box binding 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300017N15Rik; 3000003M19Rik; NFX.1; TEG-42; Tex42
Description (Vector)
Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
Gene ID
74164
Gene Name (Vector)
nuclear transcription factor, X-box binding 1
Gene Symbol
Nfx1
ORF Size (aa)
2415
ORF Size (bp)
2415 bp
RefSeq ID
NM_023739
RefSeq Synonyms
NM_023739, NM_001290449, NM_001290448, BC053709,
Species
mouse
UniGene ID
Mm.439181
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.