human NTHL1 Over-expression AAV

Name 
AAV-h-NTHL1
Cat No 
AAV-217154
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NTHL1.

AAV-217154
AAV-h-NTHL1

Ready-to-use AAV expressing Human NTHL1 (nth like DNA glycosylase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase; bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycoslyase/AP lyase; DNA glycosylase/AP lyase; endonuclease III-like protein 1; FAP3; hNTH1; nth endonuclease III-like 1; NTH1; OCTS3
Description (eCommerce)
NTHL1 is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity [taken from NCBI Entrez Gene (Gene ID: 4913)].
Description (Vector)
NTHL1 is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
Gene ID
4913
Gene Name (eCommerce)
nth like DNA glycosylase 1
Gene Name (Vector)
nth like DNA glycosylase 1
Gene Symbol
NTHL1
HGNC ID
HGNC:8028
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
915
ORF Size (bp)
915 bp
Protein Name (eCommerce)
Endonuclease III-like protein 1
RefSeq ID
NM_002528
RefSeq Synonyms
NM_002528, NM_001318194, NM_001318193, BC003014,
Research Areas
DNA Damage/Repair,Mitochondrion
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
NTHL1 is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity [taken from NCBI Entrez Gene (Gene ID: 4913)].
UniGene ID
Hs.66196
UniProt ID (eCommerce)
P78549

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.