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mouse CNTN1 shRNA silencing Adenovirus

Name 
Ad-m-CNTN1-shRNA
Cat No 
shADV-280645
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Cntn1.

shADV-280645
Ad-m-CNTN1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cntn1 (contactin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AW495098; CNTN; F3cam; usl
Description (Vector)
Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).
Gene ID
12805
Gene Name (Vector)
contactin 1
Gene Symbol
Cntn1
ORF Size (aa)
3063
ORF Size (bp)
3063 bp
RefSeq ID
NM_007727
RefSeq Synonyms
NM_007727, NM_001159648, NM_001159647, BC066864,
Species
mouse
UniGene ID
Mm.470343

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.