human NSUN5 Over-expression AAV

Name 
AAV-h-NSUN5
Cat No 
AAV-217123
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NSUN5.

AAV-217123
AAV-h-NSUN5

Ready-to-use AAV expressing Human NSUN5 (NOP2/Sun RNA methyltransferase family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NOL1; NOL1R; NSUN5A; p120; p120(NOL1); WBSCR20; WBSCR20A
Description (Vector)
NSUN5 encodes a member of the evolutionarily conserved NOL1/NOP2/Sun domain family. The encoded protein may function as a DNA methyltransferase in the nucleus. NSUN5 is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
55695
Gene Name (Vector)
NOP2/Sun RNA methyltransferase family member 5
Gene Symbol
NSUN5
HGNC ID
HGNC:16385
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_018044
RefSeq Synonyms
NM_148956, NM_018044, NM_001168348, NM_001168347, BC008084,
Species
human
UniGene ID
Hs.647060

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.