human NSMCE2 Over-expression AAV

Name 
AAV-h-NSMCE2
Cat No 
AAV-217116
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NSMCE2.

AAV-217116
AAV-h-NSMCE2

Ready-to-use AAV expressing Human NSMCE2 (NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C8orf36; E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; hMMS21; methyl methanesulfonate sensitivity gene 21; MMS21; MMS21 homolog; Non-SMC element 2 homolog; non-SMC element 2, MMS21 homolog; non-structural maintenance of chromosomes element 2 homolog; NSE2; NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; zinc finger, MIZ-type containing 7; ZMIZ7
Description (eCommerce)
The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96MF7].
Gene ID
286053
Gene Name (eCommerce)
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
Gene Name (Vector)
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
Gene Symbol
NSMCE2
HGNC ID
HGNC:26513
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
744
ORF Size (bp)
744 bp
Protein Name (eCommerce)
E3 SUMO-protein ligase NSE2
RefSeq ID
NM_173685
RefSeq Synonyms
NM_173685, BC032797,
Research Areas
Aging,Cell Cycle,Cell Division,DNA Damage/Repair,Telomeric Maintenance,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96MF7].
UniGene ID
Hs.388297
UniProt ID (eCommerce)
Q96MF7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.