human NSFL1C Over-expression AAV

Name 
AAV-h-NSFL1C
Cat No 
AAV-217113
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NSFL1C.

AAV-217113
AAV-h-NSFL1C

Ready-to-use AAV expressing Human NSFL1C (NSFL1 cofactor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ776F14.1; NSFL1 (p97) cofactor (p47); NSFL1 cofactor p47; P47; p97 cofactor p47; SHP1 homolog; UBX domain-containing protein 2C; UBX1; UBXD10; UBXN2C
Description (eCommerce)
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of NSFL1C binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments [taken from NCBI Entrez Gene (Gene ID: 55968)].
Description (Vector)
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
Gene ID
55968
Gene Name (eCommerce)
NSFL1 cofactor
Gene Name (Vector)
NSFL1 cofactor
Gene Symbol
NSFL1C
HGNC ID
HGNC:15912
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1113
ORF Size (bp)
1113 bp
Protein Name (eCommerce)
NSFL1 cofactor p47
RefSeq ID
NM_018839
RefSeq Synonyms
NM_018839, NM_016143, NM_001206736, BC002801,
Research Areas
Golgi Apparatus,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of NSFL1C binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments [taken from NCBI Entrez Gene (Gene ID: 55968)].
UniGene ID
Hs.12865
UniProt ID (eCommerce)
Q9UNZ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.