human NR2C1 Over-expression AAV

Name 
AAV-h-NR2C1
Cat No 
AAV-217044
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NR2C1.

AAV-217044
AAV-h-NR2C1

Ready-to-use AAV expressing Human NR2C1 (nuclear receptor subfamily 2 group C member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
nuclear receptor subfamily 2 group C member 1; nuclear receptor subfamily 2, group C isoform; orphan nuclear receptor TR2; Testicular receptor 2; TR2; TR2 nuclear hormone receptor
Description (eCommerce)
TR2 is an orphan nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes [taken from NCBI Entrez Gene (Gene ID: 7181].
Description (Vector)
NR2C1 encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
7181
Gene Name (eCommerce)
nuclear receptor subfamily 2 group C member 1
Gene Name (Vector)
nuclear receptor subfamily 2 group C member 1
Gene Symbol
NR2C1
HGNC ID
HGNC:7971
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
Protein Name (eCommerce)
Nuclear receptor subfamily 2 group C member 1
RefSeq ID
NM_003297
RefSeq Synonyms
NM_003297, NM_001127362, NM_001032287, BC040141,
Research Areas
Gene Expression,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TR2 is an orphan nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes [taken from NCBI Entrez Gene (Gene ID: 7181].
UniGene ID
Hs.707524
UniProt ID (eCommerce)
P13056

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AAV-h-NR2C2

Cat No: AAV-217045

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.