mouse ZFP238 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Zbtb18.
shADV-276724
Ad-m-ZFP238-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Zbtb18 (zinc finger and BTB domain containing 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RP58; Zfp238; Znf238
Description (Vector)
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Gene ID
30928
Gene Name (Vector)
zinc finger and BTB domain containing 18
Gene Symbol
Zbtb18
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_013915
RefSeq Synonyms
NM_013915, NM_001012330, BC054742, BC054529,
Species
mouse
UniGene ID
Mm.330700
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.