human NPTX2 Over-expression AAV

Name
AAV-h-NPTX2

Cat No
AAV-217009

Availability
4-5 weeks

This is an AAV expressing Human NPTX2.

AAV-217009

AAV-h-NPTX2

Ready-to-use AAV expressing Human NPTX2 (neuronal pentraxin 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NARP; NP-II; NP2

Description (Vector)

NPTX2 encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.

Gene ID

4885

Gene Name (Vector)

neuronal pentraxin 2

Gene Symbol

NPTX2

HGNC ID

HGNC:7953

ORF Size (aa)

1296

ORF Size (bp)

1296 bp

RefSeq ID

NM_002523

RefSeq Synonyms

NM_002523, BC048275, BC035339, BC034781, BC009924,

Species

human

UniGene ID

Hs.3281

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.