human NPHP4 Over-expression AAV

Name 
AAV-h-NPHP4
Cat No 
AAV-216960
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NPHP4.

AAV-216960
AAV-h-NPHP4

Ready-to-use AAV expressing Human NPHP4 (nephrocystin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
POC10; SLSN4
Description (Vector)
NPHP4 encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa.
Gene ID
261734
Gene Name (Vector)
nephrocystin 4
Gene Symbol
NPHP4
HGNC ID
HGNC:19104
ORF Size (aa)
2736
ORF Size (bp)
2736 bp
RefSeq ID
NM_015102
RefSeq Synonyms
NM_015102, NM_001291594, NM_001291593, BC040520,
Species
human
UniGene ID
Hs.462348

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.