mouse VPS25 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Vps25.
shADV-276050
Ad-m-VPS25-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Vps25 (vacuolar protein sorting 25). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110020N13Rik; AW107467; D11Wsu68e
Description (Vector)
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
Gene ID
28084
Gene Name (Vector)
vacuolar protein sorting 25
Gene Symbol
Vps25
ORF Size (aa)
531
ORF Size (bp)
531 bp
RefSeq ID
NM_026776
RefSeq Synonyms
NM_026776, NM_001284414, NM_001284412, NM_001284411, BC029181,
Species
mouse
UniGene ID
Mm.301020
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.