human NOSTRIN Over-expression AAV

Name
AAV-h-NOSTRIN

Cat No
AAV-216912

Availability
4-5 weeks

This is an AAV expressing Human NOSTRIN.

AAV-216912

AAV-h-NOSTRIN

Ready-to-use AAV expressing Human NOSTRIN (nitric oxide synthase trafficking). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DaIP2

Description (Vector)

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.(supplied by OMIM, Apr 2004)

Gene ID

115677

Gene Name (Vector)

nitric oxide synthase trafficking

Gene Symbol

NOSTRIN

HGNC ID

HGNC:20203

ORF Size (aa)

1287

ORF Size (bp)

1287 bp

RefSeq ID

NM_052946

RefSeq Synonyms

NM_052946, NM_001171632, NM_001171631, NM_001039724, BC093072, BC014189,

Species

human

UniGene ID

Hs.189780

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.