mouse UBE2T shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ube2t.
shADV-275499
Ad-m-UBE2T-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ube2t (ubiquitin-conjugating enzyme E2T). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2700084L22Rik; C80607
Description (Vector)
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.
Gene ID
67196
Gene Name (Vector)
ubiquitin-conjugating enzyme E2T
Gene Symbol
Ube2t
ORF Size (aa)
615
ORF Size (bp)
615 bp
RefSeq ID
NM_026024
RefSeq Synonyms
NM_026024, NM_001278115, BC029213,
Species
mouse
UniGene ID
Mm.284587
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.