human NMT2 Over-expression AAV

Name 
AAV-h-NMT2
Cat No 
AAV-216838
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NMT2.

AAV-216838
AAV-h-NMT2

Ready-to-use AAV expressing Human NMT2 (N-myristoyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
glycylpeptide N-tetradecanoyltransferase 2; glycylpeptide N-tetradecanoyltransferase 2 variant 3; glycylpeptide N-tetradecanoyltransferase 2 variant 4; myristoyl-CoA:protein N-myristoyltransferase 2; NMT 2; peptide N-myristoyltransferase 2; type II N-myristoyltransferase
Description (eCommerce)
Peptide N-myristoyltransferase 2 (NMT2) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue [taken from NCBI Entrez Gene (Gene ID: 9397)].
Description (Vector)
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.
Gene ID
9397
Gene Name (eCommerce)
N-myristoyltransferase 2
Gene Name (Vector)
N-myristoyltransferase 2
Gene Symbol
NMT2
HGNC ID
HGNC:7858
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
Protein Name (eCommerce)
Glycylpeptide N-tetradecanoyltransferase 2
RefSeq ID
NM_004808
RefSeq Synonyms
NM_004808, NM_001308295, BC006376,
Research Areas
Acyltransferase,Golgi Apparatus,Host-Virus Interactions,Metabolism/Metabolic Process,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,infectious_disease,metabolism,neurobiology
Species
human
Target Sentence
Peptide N-myristoyltransferase 2 (NMT2) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue [taken from NCBI Entrez Gene (Gene ID: 9397)].
UniGene ID
Hs.60339
UniProt ID (eCommerce)
O60551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.