mouse TRAFD1 shRNA silencing Adenovirus

Name 
Ad-m-TRAFD1-shRNA
Cat No 
shADV-274900
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Trafd1.

shADV-274900
Ad-m-TRAFD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Trafd1 (TRAF type zinc finger domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110008K06Rik; Fln29
Description (Vector)
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
Gene ID
231712
Gene Name (Vector)
TRAF type zinc finger domain containing 1
Gene Symbol
Trafd1
ORF Size (aa)
1731
ORF Size (bp)
1731 bp
RefSeq ID
NM_172275
RefSeq Synonyms
NM_172275, NM_001163470, BC038396,
Species
mouse
UniGene ID
Mm.20488

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.