human NLRP12 Over-expression AAV

Name 
AAV-h-NLRP12
Cat No 
AAV-216793
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NLRP12.

AAV-216793
AAV-h-NLRP12

Ready-to-use AAV expressing Human NLRP12 (NLR family pyrin domain containing 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
Description (Vector)
NLRP12 encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
Gene ID
91662
Gene Name (Vector)
NLR family pyrin domain containing 12
Gene Symbol
NLRP12
HGNC ID
HGNC:22938
ORF Size (aa)
3186
ORF Size (bp)
3186 bp
RefSeq ID
NM_144687
RefSeq Synonyms
NM_144687, NM_033297, NM_001277129, NM_001277126, BC028069,
Species
human
UniGene ID
Hs.631573

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.