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mouse TIMM13 shRNA silencing Adenovirus

Name 
Ad-m-TIMM13-shRNA
Cat No 
shADV-274215
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Timm13.

shADV-274215
Ad-m-TIMM13-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Timm13 (translocase of inner mitochondrial membrane 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D10Ertd378e; Tim9; Timm9
Description (Vector)
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Gene ID
30055
Gene Name (Vector)
translocase of inner mitochondrial membrane 13
Gene Symbol
Timm13
ORF Size (aa)
288
RefSeq ID
NM_013895
RefSeq Synonyms
NM_013895, BC011436,
Species
mouse
UniGene ID
Mm.142132

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.