mouse SWAP70 shRNA silencing Adenovirus

Name 
Ad-m-SWAP70-shRNA
Cat No 
shADV-273512
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Swap70.

shADV-273512
Ad-m-SWAP70-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Swap70 (SWA-70 protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
70kDa; AV235546
Description (Vector)
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
Gene ID
20947
Gene Name (Vector)
SWA-70 protein
Gene Symbol
Swap70
ORF Size (aa)
1758
ORF Size (bp)
1758 bp
RefSeq ID
NM_009302
RefSeq Synonyms
NM_009302, BC065136,
Species
mouse
UniGene ID
Mm.334144

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.