mouse SUV420H1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Kmt5b.
shADV-273487
Ad-m-SUV420H1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kmt5b (lysine methyltransferase 5B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA117471; C630029K18Rik; Suv4-20h1; Suv420h1
Description (Vector)
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).
Gene ID
225888
Gene Name (Vector)
lysine methyltransferase 5B
Gene Symbol
Kmt5b
ORF Size (aa)
2454
ORF Size (bp)
2454 bp
RefSeq ID
NM_144871
RefSeq Synonyms
NM_144871, NM_001167889, NM_001167888, NM_001167887, NM_001167886, NM_001167885, NM_001167884, BC075709,
Species
mouse
UniGene ID
Mm.395622
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.